Kdm6b anticorps (N-Term)

N° du produit ABIN2778610

Cet anticorps Lapin Polyclonal détecte spécifiquement Kdm6b dans WB. Il présente une réactivité envers Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin et Cobaye.

Aperçu rapide pour Kdm6b anticorps (N-Term) (ABIN2778610)

Antigène: Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Kdm6b est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Kdm6b anticorps

Épitope: N-Term

Séquence: HRAVDPPGAR AAREAFALGG LSCAGAWSSC PPHPPPRSAW LPGGRCSASI

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against JMJD3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human JMJD3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1682 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Kdm6b

Antigène: Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))

Autre désignation: JMJD3

Sujet: JMJD3 is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It plays a central role in regulation of posterior development, by regulating HOX gene expression. It is involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.
Alias Symbols: KIAA0346, JMJD3
Protein Interaction Partner: WDR5, ASH2L, RBBP5, UBC, TK1, CSNK2B, HIST1H3A, WAS, SMAD3, SMAD2, SMAD4, SMAD1,
Protein Size: 1682

Poids moléculaire: 181 kDa

ID gène: 23135

NCBI Accession: NM_001080424, NP_001073893

UniProt: O15054

Pathways: L'effet Warburg